Evidence supporting the use of: Lactobacillus salivarius
For the body system: Sinuses

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus salivarius is a probiotic bacterium naturally found in the human oral cavity, gut, and other mucosal surfaces. Its use to support sinus health is primarily based on emerging scientific evidence rather than longstanding traditional use. Several studies have explored the role of probiotics, including L. salivarius, in modulating the upper respiratory tract microbiota and immune responses. Some research suggests that L. salivarius may inhibit the growth of pathogenic bacteria associated with sinus infections, such as Streptococcus pneumoniae and Haemophilus influenzae, by producing bacteriocins and lactic acid. Additionally, there is preliminary evidence from small clinical trials and animal studies indicating that L. salivarius supplementation may help reduce inflammation and support mucosal immunity in the upper respiratory tract, potentially benefiting sinus health.

However, the available clinical evidence is limited, and most studies have small sample sizes or are performed in vitro or in animal models. While these findings are promising, large-scale, well-controlled human trials are lacking. Thus, the use of L. salivarius for sinus support is justified by scientific rationale and early evidence, but the overall strength of the evidence is currently modest (rated 2 out of 5). Further research is needed to confirm its efficacy and establish dosing protocols for sinus health.

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