Evidence supporting the use of: Magnolia biondii
For the health condition: Sinus Infection

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Magnolia biondii, known as "Xin Yi Hua" in traditional Chinese medicine (TCM), has a long-standing historical use for the treatment of sinus-related conditions, including sinusitis (sinus infection), nasal congestion, and rhinitis. The flower buds of Magnolia biondii are a key ingredient in classic TCM formulations such as "Cang Er Zi San" and "Xin Yi San," which are prescribed to "dispel wind-cold" and "open the nasal orifices." Historical texts such as the Shennong Bencao Jing and later TCM materia medica describe its use for symptoms consistent with modern sinus infections (e.g., nasal obstruction, thick nasal discharge, and headache). The traditional rationale centers around its purported ability to clear nasal passages and relieve "Qi stagnation" in the head.

While some modern pharmacological studies have investigated the anti-inflammatory and antimicrobial properties of Magnolia species, including Magnolia biondii, direct clinical evidence supporting its efficacy for treating sinus infections is limited and largely anecdotal or based on historical use. Most contemporary research focuses on related species (e.g., Magnolia officinalis), and robust, high-quality clinical trials on Magnolia biondii for sinus infections are lacking. Nevertheless, the traditional use is well documented and widely practiced in Asia.

In summary, the use of Magnolia biondii for sinus infections is primarily justified by traditional practice, with some supporting pharmacological rationale but limited high-level scientific validation at this time.

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