Evidence supporting the use of: Goldenseal
For the health condition: Sinus Infection

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Goldenseal (Hydrastis canadensis) has a long history of traditional use by Native American tribes and later by herbalists in North America, primarily for its purported antimicrobial and anti-inflammatory properties. Traditionally, goldenseal has been used as a remedy for various mucous membrane infections, including those affecting the sinuses. The main active compounds in goldenseal are berberine, hydrastine, and canadine, which have demonstrated antimicrobial activity in laboratory studies. However, most of the historical use for sinus infections is based on anecdotal evidence and traditional herbal practices rather than robust clinical trials.

There is limited scientific research specifically evaluating goldenseal for sinus infections (sinusitis). Some in vitro studies suggest that berberine can inhibit the growth of certain bacteria and may reduce inflammation, which theoretically could help with sinus infections, especially those caused or worsened by bacteria. However, clinical studies in humans supporting its effectiveness for this condition are lacking or of poor quality. As such, while goldenseal is still found in some herbal sinus remedies, its use is largely justified by tradition rather than strong scientific validation. Caution is also advised, as goldenseal can interact with various medications and may not be suitable for everyone.

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