Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Benegut Perilla (proprietary) appears to be a supplement blend that includes Perilla frutescens, a plant widely used in traditional East Asian medicine. The use of perilla for respiratory and sinus-related conditions, including sinus infections, is primarily based on traditional herbal medicine practices. In Traditional Chinese Medicine (TCM), perilla leaves are considered to have anti-inflammatory and anti-allergic properties, and are sometimes used to manage symptoms such as nasal congestion, cough, and sinus discomfort. The rationale is that perilla can help "disperse wind-cold," which is thought to contribute to upper respiratory tract symptoms.

Scientific studies on Perilla frutescens have identified some bioactive compounds, such as rosmarinic acid and flavonoids, that possess anti-inflammatory and anti-allergic activity in vitro and in animal models. However, there is limited direct clinical evidence that perilla or proprietary blends like Benegut Perilla are effective for treating or supporting sinus infections (acute or chronic rhinosinusitis) in humans. Most available studies focus on allergy symptoms rather than infection. Thus, while the traditional use is well established, scientific validation remains weak, and high-quality clinical trials in the context of sinus infection are lacking.

In summary, the use of Benegut Perilla for sinus infection is primarily justified by tradition, with only modest scientific support for related symptoms such as inflammation and allergy.

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