Evidence supporting the use of: Vitamin D
For the health condition: Senility

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin D has been investigated for its potential role in supporting cognitive function in older adults, particularly in the context of "senility," a non-specific term often referring to cognitive decline or dementia. Several observational studies have found an association between low serum vitamin D levels and an increased risk of cognitive impairment, Alzheimer's disease, and other forms of dementia. Vitamin D receptors are present in the brain, and vitamin D is believed to play a role in neuroprotection, regulation of neurotrophic factors, and reduction of inflammation, all of which may impact cognitive health.

However, randomized controlled trials (RCTs) evaluating vitamin D supplementation for the prevention or treatment of cognitive decline have generally produced mixed or modest results. Some studies suggest a slight benefit in maintaining cognitive function among those with deficiency, while others show no significant effect compared to placebo. Meta-analyses indicate that while correcting vitamin D deficiency is important for overall health, its direct effect on cognitive outcomes is limited or unclear. Most clinical guidelines do not recommend vitamin D specifically for treating cognitive decline unless deficiency is present.

In summary, while there is scientific interest and some observational evidence linking vitamin D status to cognitive health in older adults, the quality and consistency of intervention data are limited. Therefore, the evidence supporting vitamin D for the treatment of senility is rated as low (2/5), and its use should be individualized, focusing on correcting deficiency rather than as a primary treatment for cognitive decline.

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Other health conditions supported by vitamin D

Acne
Allergies (food)
Allergies (respiratory)
Alzheimer's Disease
Amenorrhea
Anemia
Anorexia
Apathy
Arrhythmia
Arteriosclerosis
Arthritis
Asthma
Autism
Autoimmune Disorders
Backache
Birth Defects (prevention)
Body Building
Broken Bones
Calcium Deficiency
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Celiac Disease
Chronic Obstructive Pulmonary Disorder
Colds (antiviral)
Colds (general)
Colds (prevention)
Colds (with fever)
Concentration (poor)
Concussions
Confusion
Congestive Heart Failure
Contagious Diseases
Convalescence
Convulsions
Cramps (menstrual)
Cramps and Spasms
Crohn's Disease
Cystic Breast Disease
Cystic Fibrosis
Dandruff
Debility
Dementia
Depression
Dermatitis
Diabetes
Diabetic Retinopathy
Erectile Dysfunction
Estrogen (low)
Fatigue
Fibroids (uterine)
Fibromyalgia Syndrome
Fibrosis
Grave's Disease
Grief and Sadness
Hair (loss or thinning)
Hair Care (general)
Hashimoto's Disease
Headache (cluster)
Heart (weakness)
Hypertension
Hypothyroid
Infection
Infection (bacterial)
Infection (viral)
Infertility
Inflammation
Inflammatory Bowel Disorders
Influenza
Injuries
Irritable Bowel Syndrome
Itching
Knees (weak)
Leaky Gut Syndrome
Leprosy
Lesions
Leukemia
Lou Gehrig's Disease
Lupus
Lymphoma
Melanoma
Memory and Brain Function
Menopause
Menstrual Irregularity
Mental Illness
Metabolic Syndrome
Migraine
Miscarriage (prevention)
Mood Swings
Multiple Sclerosis
Muscle Tone (lack of)
Muscular Dystrophy
Myasthenia Gravis
Nephritis
Nerve Damage
Nervous Exhaustion
Numbness
Nursing
Obsessive Compulsive Disorder
Oral Surgery
Osteoporosis
Pain (general remedies for)
Pancreatitis
Paralysis
Parkinson's Disease
Peripheral Neuropathy
PMS (general)
PMS Type D
PMS Type H
PMS Type P
PMS Type S
Pneumonia
Polyps
Post Partum Depression
Post Partum Weakness
Pregnancy (herbs and supplements for)
Progesterone (low)
Prostatitis
Psoriasis
Rheumatoid Arthritis
Schizophrenia
Sciatica
Seasonal Affective Disorder
Senility
Tuberculosis