Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Mahonia species, such as Mahonia aquifolium (Oregon grape), have a long history of traditional use by Native American and other herbal medicine systems for the management of minor skin injuries, including scratches and abrasions. The roots and bark contain alkaloids like berberine, which are known for their antimicrobial properties. Traditional applications typically involve poultices or infusions applied directly to the skin to help cleanse wounds, reduce inflammation, and discourage infection. There is some ethnobotanical documentation supporting these practices, especially in the context of first aid and wound care before modern antiseptics were available.

While there is a body of scientific literature confirming the antimicrobial and anti-inflammatory properties of Mahonia extracts—especially berberine—there is limited direct clinical evidence specifically evaluating their efficacy in treating minor skin injuries such as scratches and abrasions. Most studies focus on Mahonia's use for chronic skin conditions like psoriasis and eczema. Therefore, the justification for using Mahonia in this context is primarily based on tradition, with some secondary support from preclinical research on its bioactive compounds. Clinical research specifically on wound healing or infection prevention in scratches and abrasions is lacking, resulting in a moderate evidence rating.

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