Evidence supporting the use of: Devil's claw
For the health condition: Sciatica

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Devil's claw (Harpagophytum procumbens) is an herbal remedy traditionally used in African medicine for pain and inflammation. Its use for musculoskeletal pain, including sciatica, has gained some scientific interest, primarily due to its anti-inflammatory and analgesic properties attributed to its iridoid glycosides, particularly harpagoside.

Several clinical studies and systematic reviews have evaluated devil's claw for various types of back pain, which commonly includes sciatica as a symptom. A 2007 Cochrane review concluded that there is moderate evidence that preparations of devil's claw can reduce low back pain more effectively than placebo, and possibly as effectively as standard NSAIDs, though evidence is limited by small sample sizes and varying quality.

Most studies do not focus specifically on sciatica but rather on non-specific lower back pain, which can overlap with sciatic pain. However, because inflammation and nerve irritation are common to both conditions, the anti-inflammatory effects of devil's claw may offer symptomatic relief.

While promising, the evidence remains limited (rated 2/5), and larger, high-quality trials specifically targeting sciatica are lacking. Overall, devil's claw is used for sciatica based on both scientific rationale and some supportive clinical data, but it should not replace conventional treatments where indicated. Always consult a healthcare professional before starting any herbal supplement.

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