Evidence supporting the use of: Actaea spicata
For the health condition: Sciatica

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Actaea spicata (commonly known as baneberry) has been used in traditional herbal and homeopathic medicine systems, particularly in parts of Europe and Asia, to address conditions associated with nerve pain, including sciatica. The rationale behind its use is largely rooted in historical herbal practices and homeopathic materia medica, where Actaea spicata is sometimes recommended for various neuralgic and rheumatic pains affecting the limbs and lower back. However, there are no robust clinical trials, pharmacological studies, or modern scientific reviews that validate its efficacy or safety specifically for sciatica. The available literature primarily documents its use in folk medicine, with sparse references even in traditional texts. Additionally, Actaea spicata contains compounds (such as protoanemonin) that are considered toxic, and the plant is generally regarded as poisonous if ingested in significant amounts. Therefore, while there is some historical precedent for its use in conditions resembling sciatica, this is not supported by scientific evidence, and safety concerns further limit its recommendation. The evidence rating is low, reflecting the lack of well-documented, reliable support for its use in treating or supporting sciatica.

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