Evidence supporting the use of: Glycolic acid
For the health condition: Scars / Scar Tissue
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Glycolic acid is an alpha hydroxy acid (AHA) commonly used in dermatology and cosmetic skincare, primarily for its exfoliating properties. Its use for scars and scar tissue has some scientific support, mainly in the treatment of superficial acne scars and post-inflammatory hyperpigmentation rather than deep or mature scars. Glycolic acid works by increasing epidermal turnover and promoting the shedding of dead skin cells, which can help in the gradual fading of hyperpigmented marks and improving skin texture. Several clinical studies, including randomized controlled trials, have shown that glycolic acid peels and topical formulations can lead to modest improvements in the appearance of mild atrophic acne scars and pigmented scars by stimulating collagen production and promoting resurfacing of the skin (J Drugs Dermatol. 2013;12(5):e61-6). However, its effectiveness is limited for deep, hypertrophic, or keloid scars, as it does not penetrate deeply enough to remodel dense scar tissue. Most evidence is for concentration-controlled chemical peels (20–70% glycolic acid) administered under professional supervision. Over-the-counter products with lower concentrations may have only minimal effects. While glycolic acid is a well-established ingredient for skin rejuvenation and superficial scar improvement, the overall evidence base for its use in scar treatment is moderate and largely limited to minor, superficial scars. Thus, its use is scientifically justifiable for mild cases, but expectations should be tempered for more significant scarring.
Other ingredients used for Scars / Scar Tissue
AcemannanAchyranthes
Alkanna
Allantoin
Aloe vera
Alpha hydroxy acids
argan nut oil
asiaticoside
banyan
bee propolis
Brazilian peppertree
Calotropis gigantea
Cedrus libani
Centella asiatica
Centella triterpenes
collagen
Connective tissue growth factor
copaiba oil
Cyathula
Davilla rugosa
dragon\'s blood
emu oil
Ficus religiosa
Galbanum
Glycolic acid
Glycosaminoglycans
gotu kola
henna
hyaluronic acid
Hyaluronidase
Indian nightshade
jojoba oil
Kigelia africana
L-proline
Myrobalan
oriental arborvitae
Panthenol
proteolytic enzymes
Rubia cordifolia
silicon
Silk protein
Sweet Bay
Tea Tree Oil
turmeric
vitamin C
vitamin E
Witch Hazel
Zinc
Other health conditions supported by Glycolic acid
AcneAge Spots
Canker Sores
Dandruff
Gingivitis
Lesions
Psoriasis
Scars / Scar Tissue
Seborrhea
Skin (dry and/or flaky)
Skin (oily)
Skin Care (general)
Warts
Wounds and Sores
Wrinkles
