Evidence supporting the use of: Centella asiatica
For the health condition: Scars / Scar Tissue
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Centella asiatica has a long history of use in traditional medicine systems such as Ayurveda and Traditional Chinese Medicine for wound healing and the treatment of skin conditions, including scars. In the modern scientific context, several studies have investigated its effects on scar formation and tissue repair. The primary active constituents—asiaticoside, madecassoside, and asiatic acid—have demonstrated the ability to stimulate collagen synthesis and promote fibroblast proliferation, both essential processes in wound healing and scar remodeling.
Clinical studies, though limited and often small in scale, suggest that topical formulations containing Centella asiatica extracts may improve scar appearance, reduce scar thickness, and enhance overall wound healing. For example, randomized controlled trials have shown positive outcomes in the management of hypertrophic scars and keloids, as well as in post-surgical wound healing. The mechanisms appear to involve modulation of inflammation, increased antioxidant activity, and regulation of growth factors involved in tissue repair.
However, while the scientific evidence is promising and supports the traditional use of Centella asiatica for scars and scar tissue, more rigorous, large-scale clinical trials are needed to confirm efficacy and establish optimal formulations and dosages. As such, Centella asiatica's use in scar management is justified by both tradition and a moderate level of scientific validation.
Other ingredients used for Scars / Scar Tissue
Aloe veraMyrobalan
bisabolol
collagen
turmeric
gotu kola
hyaluronic acid
L-proline
silicon
vitamin C
vitamin E
Zinc
Rubia cordifolia
oriental arborvitae
asiaticoside
Achyranthes
Alpha hydroxy acids
Allantoin
Acemannan
argan nut oil
Alkanna
bee propolis
Brazilian peppertree
banyan
Centella triterpenes
Calotropis gigantea
Cyathula
Centella asiatica
Cedrus libani
Connective tissue growth factor
copaiba oil
dragon\'s blood
Davilla rugosa
emu oil
Ficus religiosa
Glycolic acid
Glycosaminoglycans
Galbanum
henna
Hyaluronidase
Indian nightshade
jojoba oil
Kigelia africana
proteolytic enzymes
Panthenol
Silk protein
Sweet Bay
Tea Tree Oil
Witch Hazel
Other health conditions supported by Centella asiatica
AbrasionsAnxiety
Anxiety Disorders
Arthritis
Backache
Bell's Palsy
Bleeding (internal)
Bruises (healing)
Burns and Scalds
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Capillary Weakness
Circulation (poor)
Convalescence
Cuts
Depression
Dermatitis
Diabetes
Edema
Fatigue
Gastritis
Gingivitis
Inflammation
Insomnia
Liver Detoxification
Memory and Brain Function
Pain (general remedies for)
Psoriasis
Scars / Scar Tissue
Stress
Ulcers
Wounds and Sores