Evidence supporting the use of: Lactobacillus casei
For the health condition: Rhinitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus casei is a probiotic bacterium that has been studied for its potential role in modulating immune responses, including those involved in allergic diseases such as rhinitis. There is some scientific evidence suggesting that certain strains of L. casei may help alleviate symptoms of allergic rhinitis by influencing the balance of Th1/Th2 immune responses and promoting regulatory T cell function. For example, small randomized controlled trials and animal studies have shown that oral supplementation with L. casei can reduce nasal symptoms and decrease inflammatory markers in patients with allergic rhinitis. However, the quality and quantity of the evidence are limited. Most studies are small, short-term, and use different strains and dosages, making it difficult to draw firm conclusions about efficacy or optimal use. Systematic reviews have noted that while probiotics, including L. casei, may have a modest benefit in allergic rhinitis, the results are inconsistent and larger, well-designed trials are needed. There is no substantial historical or traditional use of L. casei specifically for rhinitis; its use is based on emerging scientific interest in the gut-immune axis. In summary, the use of L. casei for rhinitis is supported by preliminary scientific evidence, but the overall strength of the evidence is low to moderate and further research is warranted.

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