Evidence supporting the use of: Bifidobacterium lactis
For the health condition: Rhinitis, Allergic

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bifidobacterium lactis, a probiotic bacterium commonly found in the human gastrointestinal tract, has been investigated for its immunomodulatory effects, including its potential role in alleviating symptoms of allergic rhinitis. Scientific interest stems from the ability of certain probiotics to modulate the immune response, promote regulatory T cell activity, and influence the balance between Th1 and Th2 immune responses, which are often dysregulated in allergic conditions.

Several clinical studies and randomized controlled trials have explored the efficacy of Bifidobacterium lactis (often in combination with other probiotic strains) in reducing the severity of allergic rhinitis symptoms, such as sneezing, nasal congestion, and rhinorrhea. For example, some trials have suggested that supplementation with B. lactis may help decrease the levels of IgE and inflammatory cytokines, thereby reducing allergic inflammation. However, the results are mixed, with some studies showing modest benefits and others demonstrating no significant improvement compared to placebo.

While the mechanistic rationale for using B. lactis in allergic rhinitis is plausible—given its effect on gut and systemic immunity—the current body of clinical evidence is limited and of variable quality. Most studies have used multi-strain probiotic formulations, making it difficult to attribute observed effects specifically to B. lactis. As such, the evidence supporting its use in allergic rhinitis is considered preliminary and not robust enough for strong clinical recommendations. Further well-designed, large-scale studies are warranted to confirm these potential benefits.

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