Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Soy unsaponifiables are a mixture of compounds extracted from soybeans that have been investigated for their potential anti-inflammatory and chondroprotective effects. The most common clinical use is in osteoarthritis, but there is some evidence regarding rheumatoid arthritis (RA) as well. Several small-scale studies and preclinical models suggest that soy unsaponifiables may modulate inflammatory pathways, reduce cytokine production, and provide symptom relief in inflammatory joint diseases. However, the majority of published clinical trials have focused on osteoarthritis, with only limited and preliminary data pertaining directly to RA. For example, some laboratory studies indicate that soy unsaponifiables can inhibit pro-inflammatory mediators involved in RA pathogenesis, but robust, large-scale randomized controlled trials in RA patients are lacking.

Overall, while there is a scientific rationale and some early supportive evidence for the use of soy unsaponifiables in inflammatory arthritis, the quality and quantity of evidence for their efficacy in rheumatoid arthritis specifically is limited. Current rheumatology guidelines do not recommend soy unsaponifiables for RA, and their use is considered adjunctive at best. More rigorous research is needed to validate their role in RA management.

More about Soy unsaponifiables
More about Rheumatoid Arthritis

Other ingredients used for Rheumatoid Arthritis

adrenal cortex
alfalfa
algal oil
alpha-linolenic acid (ALA)
alpha-pinene
anthocyanins
ashwagandha
astaxanthin
borage oil
celery
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
dong quai root
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fisetin
fish protein
gamma linolenic acid (GLA)
gamma tocopherol
genistein
ginger
green lipped mussel
krill oil
luteolin
methylsulfonylmethane (MSM)
myristoleate
omega-3 fatty acids
phospholipids
resveratrol
rose hips
sardines
slippery elm bark
sulforaphane glucosinolate
Urolithin A
vitamin B6
vitamin C
vitamin D
vitamin D3
watercress
white willow
alpinia galangal
smilax
fumaria parviflora
lingusticum wallichii
amber
teasel
guelder rose
gentiana macrophylla
abies spectabilis
AMP-activated protein kinase (AMPK)
clematis
15,16-Dihydrotanshinone I
Aralia
akebia
Antler
Apigenin
Abrus
Andrographolide
Amentoflavone
Alpha-Lipoic Acid
anthocyanidins
Ampelopsin
Actaea spicata
Acetylsalicylic acid
Arjunic Acid
Apocynin
Arctiin
Astragalin
Boswellic Acid
Baicalein
Bogbean
Boswellia
Black willow
Barbasco
bovine cartilage / glycosaminoglycan
Baicalin
Black Hellebore
Bee venom
Bergenia
Cod Liver Oil
Cortisol
Clerodendrum phlomidis
Cyanidin
Chinese Fleeceflower
Chinese Pond Turtle
Chuchuhuasi
Cetylated Fatty Acids
C-Phycocyanin
Cannabidiol
Carnosic acid
Docosahexaenoic Acid
Dihomo-gamma-linolenic acid
Eicosatetraenoic acid
Eicosapentaenoic Acid
Evening Primrose Oil
Fructoborate
Flemingia philippinensis
Frankincense
Flavanols
Flavones
Ginkgetin

Other health conditions supported by Soy unsaponifiables

Arthritis
Cartilage Damage
Rheumatoid Arthritis

Products containing Soy unsaponifiables

We currently have no products on Caring Sunshine that contain this ingredient.