Evidence supporting the use of: Polyunsaturated fat
For the health condition: Rheumatoid Arthritis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Polyunsaturated fats (PUFAs), particularly omega-3 fatty acids such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) found in fish oil, have been studied for their potential benefits in rheumatoid arthritis (RA). The scientific rationale is based on their anti-inflammatory properties. PUFAs are precursors to bioactive lipid mediators that can reduce the production of pro-inflammatory cytokines and eicosanoids, which play a role in the pathogenesis of RA. Several randomized controlled trials and meta-analyses have shown that supplementation with omega-3 PUFAs can modestly reduce joint pain, morning stiffness, and the need for non-steroidal anti-inflammatory drugs (NSAIDs) in RA patients. However, the magnitude of benefit is generally moderate, and omega-3 supplementation is regarded as an adjunct rather than a primary therapy. There is less evidence supporting the use of omega-6 PUFAs, and in some cases, high intake of omega-6 fatty acids may be pro-inflammatory. Most clinical guidelines acknowledge the modest benefits of omega-3 PUFA supplementation as part of dietary management in RA. The evidence does not support PUFAs as a replacement for disease-modifying antirheumatic drugs (DMARDs), but they may offer supportive benefits in symptom management.

More about polyunsaturated fat
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Other ingredients used for Rheumatoid Arthritis

adrenal cortex
Alfalfa
algal oil
alpha-linolenic acid (ALA)
alpha-pinene
anthocyanins
ashwagandha
astaxanthin
borage oil
celery
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaenoic acid)
diallyl disulfide (DADS)
dong quai root
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fisetin
fish protein
gamma linolenic acid (GLA)
gamma tocopherol
genistein
ginger
green-lipped mussel
krill oil
luteolin
Methylsulfonylmethane (MSM)
Myristoleate
omega-3 fatty acids
phospholipids
resveratrol
rose hips
slippery elm bark
sulforaphane glucosinolate
Urolithin A
vitamin B6
vitamin C
vitamin D
vitamin D3
Watercress
white willow
alpinia galangal
smilax
Fumaria parviflora
Szechuan lovage
amber
teasel
guelder rose
Gentiana macrophylla
Abies spectabilis
AMP-activated protein kinase (AMPK)
clematis
15,16-Dihydrotanshinone I
Aralia
Akebia
antler
apigenin
Abrus
andrographolide
amentoflavone
alpha-lipoic acid
anthocyanidins
ampelopsin
Actaea spicata
arjunic acid
apocynin
arctiin
astragalin
Boswellic Acid
baicalein
bogbean
Boswellia
Black willow
barbasco
bovine cartilage / glycosaminoglycan
baicalin
Black Hellebore
bee venom
Bergenia
cod liver oil
cortisol
Clerodendrum phlomidis
cyanidin
Chinese fleeceflower
Chinese pond turtle
chuchuhuasi
Cetylated Fatty Acids
C-phycocyanin
cannabidiol
carnosic acid
docosahexaenoic Acid
Dihomo-gamma-linolenic acid
Eicosatetraenoic acid
eicosapentaenoic acid
evening primrose oil
fat liver oil
fructoborate
Flemingia philippinensis
frankincense
flavanols
flavones
ginkgetin
Gypenoside
horse gram
Hyperoside
Hellebore
hydroxytyrosol
Harpagoside
Jatropha macrantha
Kaempferol
mangiferin
Myricetin
madder
Marine fat
Nobiletin
Osthole
Puerarin
Piper chaba
Phaeophyceae
proteoglycans
Polydatin
polyunsaturated fat
Palmitoylethanolamide (PEA)
Qin Jiao
Silkmoth
Schizochytrium Oil
Schizochytrium
Salicin
Salmon Oil
Salvianolic acid
Sinomenium acutum
Semecarpus anacardium
saponins
Shilajit
Stearidonic acid
Sulforaphane
Taxillus chinensis
Tanshinone
Uncaria
Ursolic Acid
Withanolides

Products containing polyunsaturated fat

We currently have no products on Caring Sunshine that contain this ingredient.