Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Marine fat, particularly from sources like fish oil, is used to support the treatment of Rheumatoid Arthritis (RA) due to its high content of omega-3 polyunsaturated fatty acids, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Multiple randomized controlled trials and meta-analyses have demonstrated that supplementation with marine-derived omega-3 fatty acids can reduce joint pain, morning stiffness, and the number of tender joints in patients with RA. The proposed mechanism involves the anti-inflammatory effects of omega-3s, which are thought to decrease production of pro-inflammatory eicosanoids and cytokines, thereby modulating immune response and inflammation associated with RA. Notably, the American College of Rheumatology and other professional organizations acknowledge the potential benefit of fish oil supplementation as an adjunct to standard pharmacologic therapies for RA, though they do not recommend it as a standalone treatment. The degree of benefit is generally considered modest, and effects can take several months to become noticeable. It is important to distinguish that the evidence specifically relates to well-characterized fish oil or marine omega-3 supplements, rather than "marine fat (unspecified)," as the latter term could include various marine-derived fats with differing compositions and potential contaminants. Therefore, while there is scientific evidence supporting the use of certain forms of marine fat (namely fish oil) in RA, the strength of evidence is moderate, and proper formulation and dosing are important considerations.

More about Marine fat (unspecified)
More about Rheumatoid Arthritis

Other ingredients used for Rheumatoid Arthritis

Other health conditions supported by Marine fat (unspecified)

Products containing Marine fat (unspecified)