Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Marine fat, particularly from sources such as fish oil (rich in omega-3 fatty acids like EPA and DHA), is scientifically studied for its effects on rheumatoid arthritis (RA). Multiple randomized controlled trials and meta-analyses have shown that supplementation with fish oil can reduce the number of tender joints, duration of morning stiffness, and overall pain in individuals with RA. The anti-inflammatory properties of omega-3 fatty acids are believed to be the main mechanism, as they compete with arachidonic acid (an omega-6 fatty acid) in the production of pro-inflammatory eicosanoids. This shift can lead to reduced inflammatory mediators, which is beneficial in autoimmune conditions like RA.

While the effect sizes are generally moderate, and marine fat is not a replacement for disease-modifying antirheumatic drugs (DMARDs), its use as an adjunct therapy is supported by clinical evidence. Systematic reviews (e.g., Goldberg & Katz, 2007; Miles & Calder, 2012) acknowledge modest improvements in clinical outcomes and reductions in NSAID use with fish oil supplementation. Most guidelines view fish oil as a complementary intervention rather than a core treatment, reflecting the moderate (not strong) level of evidence. The use of other types of marine fat (e.g., seal or whale blubber) is less studied and not commonly recommended due to lack of data and potential contaminants.

In summary, the use of marine fat (primarily as fish oil) in supporting rheumatoid arthritis is scientifically validated to a moderate extent, with clinical benefits recognized as adjunctive rather than primary therapy.

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