Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Honduran Sarsaparilla (Smilax spp.), also known as Jamaican or Honduran sarsaparilla, has a long history of use in traditional medicine systems, particularly in Central and South America. It has been used for centuries as a remedy for various inflammatory conditions, including rheumatoid arthritis (RA). Traditional herbalists and indigenous practitioners employed sarsaparilla roots in teas and decoctions to help reduce joint pain, swelling, and stiffness associated with arthritis and other rheumatic disorders.

The traditional rationale for its use is based on the observation that sarsaparilla contains various phytochemicals—such as saponins, flavonoids, and sterols—which are thought to have anti-inflammatory and immune-modulating properties. Despite these traditional uses, modern scientific studies on sarsaparilla’s efficacy specifically for rheumatoid arthritis are very limited. The available evidence mostly consists of in vitro or animal studies suggesting possible anti-inflammatory effects, but there is a lack of well-designed human clinical trials directly evaluating its benefit in RA patients.

In summary, the use of Honduran sarsaparilla for rheumatoid arthritis is primarily supported by traditional herbal medicine practices, with only weak indirect scientific evidence and no robust clinical validation as of 2024.

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