Evidence supporting the use of: Hellebore
For the health condition: Rheumatoid Arthritis
Synopsis
Source of validity: Traditional
Rating (out of 5): 1
Hellebore, particularly species such as Helleborus niger and Helleborus officinalis, has a history of use in traditional European herbal medicine dating back to ancient Greece and Rome. Historically, hellebore preparations were used to treat a variety of ailments, including joint pain and inflammatory conditions, which today would include rheumatoid arthritis (RA). These uses were often based on the plant’s strong purgative and emetic properties, as well as a belief in its ability to “cleanse” the body of disease. However, hellebores are highly toxic, containing compounds such as helleborin and hellebrin, which can cause severe gastrointestinal and cardiac effects. Modern scientific research does not support the safety or efficacy of hellebore for RA; clinical trials are lacking, and its toxicity makes it unsuitable for therapeutic use. Thus, while hellebore’s use for RA is rooted in tradition, there is minimal scientific evidence to support it, and significant safety concerns exist. As such, it is not recommended in contemporary herbal practice for rheumatoid arthritis.
Other ingredients used for Rheumatoid Arthritis
adrenal cortexAlfalfa
algal oil
alpha-linolenic acid (ALA)
alpha-pinene
anthocyanins
ashwagandha
astaxanthin
borage oil
celery
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaenoic acid)
diallyl disulfide (DADS)
dong quai root
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fisetin
fish protein
gamma linolenic acid (GLA)
gamma tocopherol
genistein
ginger
green-lipped mussel
krill oil
luteolin
Methylsulfonylmethane (MSM)
Myristoleate
omega-3 fatty acids
phospholipids
resveratrol
rose hips
slippery elm bark
sulforaphane glucosinolate
Urolithin A
vitamin B6
vitamin C
vitamin D
vitamin D3
Watercress
white willow
alpinia galangal
smilax
Fumaria parviflora
Szechuan lovage
amber
teasel
guelder rose
Gentiana macrophylla
Abies spectabilis
AMP-activated protein kinase (AMPK)
clematis
15,16-Dihydrotanshinone I
Aralia
Akebia
antler
apigenin
Abrus
andrographolide
amentoflavone
alpha-lipoic acid
anthocyanidins
ampelopsin
Actaea spicata
arjunic acid
apocynin
arctiin
astragalin
Boswellic Acid
baicalein
bogbean
Boswellia
Black willow
barbasco
bovine cartilage / glycosaminoglycan
baicalin
Black Hellebore
bee venom
Bergenia
cod liver oil
cortisol
Clerodendrum phlomidis
cyanidin
Chinese fleeceflower
Chinese pond turtle
chuchuhuasi
Cetylated Fatty Acids
C-phycocyanin
cannabidiol
carnosic acid
docosahexaenoic Acid
Dihomo-gamma-linolenic acid
Eicosatetraenoic acid
eicosapentaenoic acid
evening primrose oil
fat liver oil
fructoborate
Flemingia philippinensis
frankincense
flavanols
flavones
ginkgetin
Gypenoside
horse gram
Hyperoside
Hellebore
hydroxytyrosol
Harpagoside
Jatropha macrantha
Kaempferol
mangiferin
Myricetin
madder
Marine fat
Nobiletin
Osthole
Puerarin
Piper chaba
Phaeophyceae
proteoglycans
Polydatin
polyunsaturated fat
Palmitoylethanolamide (PEA)
Qin Jiao
Silkmoth
Schizochytrium Oil
Schizochytrium
Salicin
Salmon Oil
Salvianolic acid
Sinomenium acutum
Semecarpus anacardium
saponins
Shilajit
Stearidonic acid
Sulforaphane
Taxillus chinensis
Tanshinone
Uncaria
Ursolic Acid
Withanolides