Evidence supporting the use of: Flavanols (various)
For the health condition: Rheumatoid Arthritis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Flavanols, a subclass of flavonoids found in foods like cocoa, tea, apples, and berries, have been investigated for their anti-inflammatory and antioxidant properties, which are theoretically relevant to the treatment of Rheumatoid Arthritis (RA). Several in vitro and animal studies suggest that flavanols can inhibit pro-inflammatory cytokines (such as TNF-α and IL-6), reduce oxidative stress, and modulate immune cell activity, all of which are implicated in RA pathogenesis. Human evidence, however, remains limited. Some small clinical studies and pilot trials have reported modest improvements in markers of inflammation and patient-reported outcomes in people with RA or similar inflammatory conditions after consuming flavanol-rich foods or supplements. For example, green tea catechins and cocoa flavanols have been shown to reduce C-reactive protein (CRP) levels and joint tenderness in a few trials, but these studies generally have small sample sizes, short durations, and sometimes lack rigorous controls. Larger, high-quality randomized controlled trials are lacking. As a result, while there is a scientific rationale and preliminary data supporting the potential benefit of flavanols in RA, the overall evidence is weak-to-moderate and insufficient to recommend their use as a primary or adjunct therapy. More robust clinical research is needed to establish their efficacy and safety in RA management.

More about flavanols (various)
More about Rheumatoid Arthritis

Other ingredients used for Rheumatoid Arthritis

adrenal cortex
Alfalfa
algal oil
alpha-linolenic acid (ALA)
alpha-pinene
anthocyanins
ashwagandha
astaxanthin
borage oil
celery
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaenoic acid)
diallyl disulfide (DADS)
dong quai root
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fisetin
fish protein
gamma linolenic acid (GLA)
gamma tocopherol
genistein
ginger
green-lipped mussel
krill oil
luteolin
Methylsulfonylmethane (MSM)
Myristoleate
omega-3 fatty acids
phospholipids
resveratrol
rose hips
sardines
slippery elm bark
sulforaphane glucosinolate
Urolithin A
vitamin B6
vitamin C
vitamin D
vitamin D3
Watercress
white willow
alpinia galangal
smilax
Fumaria parviflora
Szechuan lovage
amber
teasel
guelder rose
Gentiana macrophylla
Abies spectabilis
AMP-activated protein kinase (AMPK)
clematis
15,16-Dihydrotanshinone I
Aralia
Akebia
antler
apigenin
Abrus
andrographolide
amentoflavone
alpha-lipoic acid
anthocyanidins
ampelopsin
Actaea spicata
arjunic acid
apocynin
arctiin
astragalin
Boswellic Acid
baicalein
bogbean
Boswellia
Black willow
barbasco
bovine cartilage / glycosaminoglycan
baicalin
Black Hellebore
bee venom
Bergenia
cod liver oil
cortisol
Clerodendrum phlomidis
cyanidin
Chinese fleeceflower
Chinese pond turtle
chuchuhuasi
Cetylated Fatty Acids
C-phycocyanin
cannabidiol
carnosic acid
docosahexaenoic Acid
Dihomo-gamma-linolenic acid
Eicosatetraenoic acid
eicosapentaenoic acid
evening primrose oil
fat liver oil
fructoborate
Flemingia philippinensis
frankincense
flavanols
flavones
ginkgetin
Gypenoside
horse gram
Hyperoside
Hellebore
hydroxytyrosol
Harpagoside
Jatropha macrantha
Kaempferol
mangiferin
Myricetin
madder
Marine fat
Nobiletin
Osthole
Puerarin
Piper chaba
Phaeophyceae
proteoglycans
Polydatin
polyunsaturated fat
Palmitoylethanolamide (PEA)
Qin Jiao
Silkmoth
Schizochytrium Oil
Schizochytrium
Salicin
Salmon Oil
Salvianolic acid
Sinomenium acutum
Semecarpus anacardium
saponins
Shilajit
Stearidonic acid
Sulforaphane
Taxillus chinensis
Tanshinone
Uncaria
Ursolic Acid
Withanolides

Products containing flavanols (various)

We currently have no products on Caring Sunshine that contain this ingredient.