Evidence supporting the use of: Black Hellebore
For the health condition: Rheumatoid Arthritis
Synopsis
Source of validity: Traditional
Rating (out of 5): 1
Black Hellebore (Helleborus niger) has a long history of use in traditional herbal medicine, particularly in Europe. Historically, it was used for a variety of ailments, including as a purgative and treatment for mental disorders, and in some cases, as a remedy for rheumatism or chronic joint pain—conditions that would today often be classified under rheumatoid arthritis. However, there is scant reliable evidence to support its efficacy for rheumatoid arthritis specifically. The rationale for its use in this context was primarily based on its purported anti-inflammatory and analgesic properties, as well as its general role as a "detoxifying" agent in traditional medicine systems.
It is important to note that Black Hellebore contains potent and toxic compounds (such as glycosides like helleborin and hellebrin), which can cause serious side effects including vomiting, diarrhea, cardiac disturbances, and even death. Because of these risks, its use has largely fallen out of favor in modern herbal medicine, and it is not considered safe for internal use today. There are no robust clinical trials or scientific studies demonstrating benefit for rheumatoid arthritis, so the evidence remains anecdotal and historical, with a rating of 1 for evidence due to traditional reports only.
In summary, while Black Hellebore has a tradition of use for rheumatic conditions, this is not supported by modern scientific research, and its toxicity outweighs any potential benefit.
Other ingredients used for Rheumatoid Arthritis
adrenal cortexalfalfa
algal oil
alpha-linolenic acid (ALA)
alpha-pinene
anthocyanins
ashwagandha
astaxanthin
borage oil
celery
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
dong quai root
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fisetin
fish protein
gamma linolenic acid (GLA)
gamma tocopherol
genistein
ginger
green lipped mussel
krill oil
luteolin
methylsulfonylmethane (MSM)
myristoleate
omega-3 fatty acids
phospholipids
resveratrol
rose hips
sardines
slippery elm bark
sulforaphane glucosinolate
Urolithin A
vitamin B6
vitamin C
vitamin D
vitamin D3
watercress
white willow
alpinia galangal
smilax
fumaria parviflora
lingusticum wallichii
amber
teasel
guelder rose
gentiana macrophylla
abies spectabilis
AMP-activated protein kinase (AMPK)
clematis
15,16-Dihydrotanshinone I
Aralia
akebia
Antler
Apigenin
Abrus
Andrographolide
Amentoflavone
Alpha-Lipoic Acid
anthocyanidins
Ampelopsin
Actaea spicata
Acetylsalicylic acid
Arjunic Acid
Apocynin
Arctiin
Astragalin
Boswellic Acid
Baicalein
Bogbean
Boswellia
Black willow
Barbasco
bovine cartilage / glycosaminoglycan
Baicalin
Black Hellebore
Bee venom
Bergenia
Cod Liver Oil
Cortisol
Clerodendrum phlomidis
Cyanidin
Chinese Fleeceflower
Chinese Pond Turtle
Chuchuhuasi
Cetylated Fatty Acids
C-Phycocyanin
Cannabidiol
Carnosic acid
Docosahexaenoic Acid
Dihomo-gamma-linolenic acid
Eicosatetraenoic acid
Eicosapentaenoic Acid
Evening Primrose
Other health conditions supported by Black Hellebore
Abdominal PainAsthma
Backache
Depression
Dizziness
Edema
Epilepsy
Fever
Gout
Headache (general)
Headache (tension)
Hemorrhoids
Inflammation
Influenza
Menstrual Irregularity
Migraine
Nausea and Vomiting
Nervous Exhaustion
Neuralgia and Neuritis
Pain (general remedies for)
Rheumatoid Arthritis
Wounds and Sores