Asparagus adscendens (commonly known as Safed Musli) is used in traditional Ayurvedic and Unani medicine systems for a variety of health conditions, including as a general tonic and for its purported anti-inflammatory effects. However, with regard to Rheumatoid Arthritis (RA), the use of Asparagus adscendens is primarily based on traditional beliefs rather than robust scientific evidence. Traditional texts and ethnobotanical surveys sometimes mention this plant for musculoskeletal complaints, and its root extracts are reputed to possess anti-inflammatory and immunomodulatory properties, which are relevant to RA.

Despite these traditional claims, there is a significant lack of direct scientific studies—either preclinical or clinical—specifically evaluating the efficacy or safety of Asparagus adscendens in the treatment or management of Rheumatoid Arthritis. The limited available research has mostly focused on other properties such as aphrodisiac or adaptogenic effects, not on autoimmune or rheumatic conditions. A few in vitro or animal studies on related Asparagus species suggest potential anti-inflammatory actions, but these findings cannot be directly extrapolated to Asparagus adscendens or RA in humans.

In summary, the use of Asparagus adscendens for Rheumatoid Arthritis is justified by traditional usage rather than by solid scientific validation. The overall evidence supporting its use for this specific condition is very weak (rated 1 out of 5).