Synopsis

Source of validity: Traditional
Rating (out of 5): 1

American Bittersweet (Celastrus scandens) has a history of traditional use among Native American tribes and early settlers in North America, primarily as a topical remedy for skin conditions and sometimes for rheumatism-related complaints. Ethnobotanical records indicate the use of bittersweet bark or berries in poultices or infusions applied to aching joints and muscles, including those affected by what would now be called rheumatoid arthritis. However, these uses are based almost entirely on anecdotal practice and oral tradition rather than clinical evaluation.

There is no robust scientific evidence, such as controlled clinical trials or pharmacological studies, to support the efficacy or safety of American Bittersweet for treating rheumatoid arthritis. Modern phytochemical analysis has identified some compounds with potential biological activity in the plant, but their relevance to inflammation or autoimmune disease in humans has not been established. Furthermore, American Bittersweet can be toxic if ingested in significant quantities, raising safety concerns.

In summary, the use of American Bittersweet for rheumatoid arthritis is rooted in traditional herbal medicine rather than scientific validation, and current evidence supporting its effectiveness is weak to nonexistent.

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