Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Yohimbe (Pausinystalia yohimbe) has a long history of traditional use, particularly in West African medicine, as an aphrodisiac and a remedy for sexual dysfunction. The bark of the yohimbe tree was used to enhance libido and improve sexual performance, especially among men. The primary active compound, yohimbine, was later isolated and became the subject of clinical interest. In the early to mid-20th century, yohimbine hydrochloride was prescribed in some countries for erectile dysfunction, although the clinical evidence supporting its efficacy is mixed and often limited by small sample sizes or methodological issues. While some studies have suggested mild benefits for erectile function, others have found little to no effect compared to placebo. Yohimbe is rarely used as a first-line therapy today due to the development of more effective and safer medications (e.g., phosphodiesterase inhibitors like sildenafil). Additionally, yohimbe can cause significant side effects such as increased blood pressure, anxiety, and heart palpitations. Regulatory agencies in some countries have restricted its sale due to safety concerns. Overall, while yohimbe’s reputation as a sexual tonic is primarily rooted in traditional use, there is some, though not robust, scientific evidence for its effects on the reproductive system, mainly concerning male sexual function.

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