Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E has a well-established role as an antioxidant, and it has been studied for its effects on reproductive health, particularly in animal models and some human studies. Historically, its name (“tocopherol”) is derived from Greek words meaning "to bear offspring," reflecting early findings that it was essential for reproduction in rats. In humans, vitamin E deficiency is rare but has been associated with infertility and reproductive issues. Some studies have investigated the potential of vitamin E supplementation to improve sperm quality and motility in men with infertility, with mixed results. For example, a few small clinical trials suggest vitamin E may reduce oxidative stress in seminal fluid and benefit sperm parameters, but systematic reviews find the overall evidence is limited and inconclusive. In women, there is less direct evidence of benefit, though its antioxidant properties are hypothesized to support general reproductive health by protecting cells from oxidative damage. Major clinical guidelines do not recommend vitamin E supplementation specifically for reproductive support in the absence of deficiency. In summary, while there is a scientific basis for vitamin E’s role in reproductive physiology and some supportive findings, robust clinical evidence for supplementation to enhance reproductive function in healthy individuals is limited.

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