Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Vitamin E, including tocotrienols (though most research focuses on tocopherols), has a long history of traditional use for supporting reproductive health. The discovery of Vitamin E itself is rooted in reproductive research: in the 1920s, rats fed a diet lacking Vitamin E became infertile, and supplementation was shown to restore fertility. Because of this, Vitamin E was sometimes called the “fertility vitamin.” Traditional and historical uses have thus associated Vitamin E with reproductive health in both men and women, including claims of improved sperm quality and reduced risk of miscarriage. However, modern scientific evidence specifically supporting tocotrienols (as opposed to tocopherols) for reproductive health is limited. Most clinical studies examining reproductive outcomes have used alpha-tocopherol, not tocotrienol forms. Some animal and cell studies suggest antioxidant effects of tocotrienols may protect reproductive tissues from oxidative stress, but direct clinical evidence in humans is lacking. Therefore, while there is a foundation in tradition and some mechanistic rationale, robust scientific validation—especially for tocotrienols—is not currently established. The evidence level is thus rated as 2, reflecting traditional use with limited scientific corroboration specific to tocotrienols.

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