Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin E, including its esterified form tocopheryl succinate, has a scientifically supported role in the functioning of the reproductive system, though the evidence is moderate. Historically, the term "tocopherol" itself is derived from Greek, meaning "to bear offspring," reflecting early observations that rats deprived of vitamin E became infertile. In humans, vitamin E is recognized as an important antioxidant, protecting cell membranes—including those of reproductive organs—from oxidative damage. Several studies have investigated the impact of vitamin E supplementation on male fertility, showing that it can improve sperm motility and reduce oxidative stress in semen, potentially benefiting men with infertility related to oxidative damage. Some clinical trials have reported improvements in sperm quality and increased pregnancy rates when vitamin E is used alone or in combination with other antioxidants. In females, vitamin E's role is less well established, but it is thought to support endometrial health and may reduce oxidative stress that can affect fertility. However, the evidence is not strong enough to recommend vitamin E supplementation for all individuals seeking to enhance reproductive health, and the benefits are most evident in specific subgroups such as those with documented deficiencies or oxidative stress-related infertility. Overall, while vitamin E is important for reproductive health and there is moderate scientific support for its use, it should be considered as part of a broader approach to reproductive wellness.

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