Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E (alpha-tocopherol) has been traditionally associated with reproductive health, and its name is partly derived from its early identification as a "fertility factor" in animal studies. Early research in the 1920s and 1930s demonstrated that Vitamin E deficiency led to infertility and fetal resorption in rodents, which established its reputation as a critical nutrient for reproduction. These findings laid the foundation for its traditional use in supporting reproductive function, particularly in males and females experiencing fertility issues.

In humans, the evidence is less clear. While some observational studies suggest that Vitamin E may improve certain parameters of male fertility, such as sperm motility and quality, the evidence from randomized controlled trials is limited and somewhat inconsistent. For example, some studies have shown that supplementation with Vitamin E, often in combination with other antioxidants, may reduce oxidative stress in semen and improve sperm function, potentially benefiting couples experiencing infertility. However, systematic reviews and meta-analyses generally conclude that there is only modest or insufficient evidence supporting Vitamin E's effectiveness as a standalone therapy for infertility in men or women.

In summary, while there is a historical and scientific basis for the use of Vitamin E in supporting reproductive health, especially due to its antioxidant properties, robust evidence in humans is limited. Therefore, its use for this purpose is only weakly supported by scientific data.

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