Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin B9, commonly known as folate (naturally occurring) or folic acid (synthetic form), is scientifically validated as essential for supporting the reproductive system, particularly in women of childbearing age. Folate plays a critical role in DNA synthesis, repair, and methylation, all of which are crucial during periods of rapid cell division and growth, such as pregnancy. Numerous clinical studies and public health data have shown that adequate folate intake before conception and during early pregnancy significantly reduces the risk of neural tube defects (NTDs) in the developing fetus. As a result, many countries mandate folic acid fortification in food products and recommend supplementation for women planning pregnancy.

Additionally, folate deficiency has been associated with infertility, recurrent pregnancy loss, and poor pregnancy outcomes. In men, some emerging evidence suggests that folate may influence sperm quality and DNA integrity, though the data are less robust compared to women. The U.S. Centers for Disease Control and Prevention (CDC), World Health Organization (WHO), and major obstetric and gynecological societies endorse the use of folic acid for reproductive health based on extensive scientific evidence. Thus, the use of Vitamin B9 to support the reproductive system is strongly grounded in scientific research, especially regarding fetal development and maternal health.

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