Evidence supporting the use of: Tongkat ali
For the body system: Reproductive System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Tongkat ali (Eurycoma longifolia) is a traditional Southeast Asian herbal remedy widely used for enhancing male fertility, libido, and overall reproductive health. Recent scientific research has begun to validate some of these traditional uses. Several clinical studies and meta-analyses indicate that tongkat ali supplementation may improve several parameters of male reproductive health, including sperm motility, sperm concentration, and semen volume, particularly in subfertile men. Some randomized controlled trials have shown increases in serum testosterone levels in men who used tongkat ali extracts, potentially mediating improvements in sexual function and libido.

Animal studies have also demonstrated increased testicular function and improved spermatogenesis after tongkat ali administration. The proposed mechanisms include modulation of the hypothalamic-pituitary-gonadal axis and reduction of cortisol, leading to improved testosterone synthesis. While the majority of studies focus on male reproductive benefits, evidence for effects in women is limited and less conclusive.

Nevertheless, the overall quality of evidence is moderate (rated 3/5), as most studies have small sample sizes, short durations, and varying extract standardizations. Larger, longer-term randomized controlled trials are needed to further confirm efficacy and safety. In summary, tongkat ali is supported both by tradition and a growing—though not yet robust—body of scientific evidence for supporting male reproductive system health.

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Other ingredients that support Reproductive System

Acetyl L-carnitine
amino acids
ashwagandha
beta-sitosterol
black cohosh
bovine
bovine liver
broccoli
calcium
chaste tree
Chinese salvia root
choline
coenzyme Q10 (CoQ10)
turmeric
damiana
DHA (docosahexaenoic acid)
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
EPA (eicosapentaenoic acid)
evening primrose oil
fennel
fenugreek
fish protein
flaxseed
folate
gamma linolenic acid (GLA)
ginger
ginseng
gokhru
hops
inositol
iodine
iron
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
L-arginine
l-carnitine
Lactobacillus crispatus
Lactobacillus jensenii
licorice root
lignans
linoleic acid (LA)
maca
magnesium
Marine lipid
Melatonin
Moringa
Motherwort
Muira puama
omega-3 fatty acids
omega-6 fatty acids
pomegranate
protein
pumpkin
quail egg
raspberry
rehmannia glutinosa
saffron
saw palmetto
selenium
selenium
soybean
spearmint leaf
Tongkat ali
tribulus
vitamin A
vitamin B
vitamin D
vitamin E
vitamin E
seaweed
Water
Wild yam
Zinc
sarsaparilla
red clover
suma
squawvine
Mugwort
nut grass
anise
punarnava
smilax
chaff flower
Szechuan lovage
Yarrow
cistanche
dioscorea
dodder
eucommia
ganoderma
lotus seed
Morinda
royal jelly
equol (proprietary)
guelder rose
trace minerals
anemarrhena asphodeloides
purslane
barrenwort
shepherd's purse
Wood betony
hypothalamus
herbal blend (proprietary)
Yohimbe
25-d-spirosta-3, 5-diene
5-methyltetrahydrofolate glucosamine
8-Prenylnaringenin
antler
arachidonic acid
Achyranthes
anamu
Alchemilla
Aletris
Anserina
Aerva lanata
Agrimonia pilosa
Agnuside
Ashoka
Abuta
Allium tuberosum
animal protein
blue cohosh
babchi
Baliospermum
black galingale
beef
Beef liver
bugbane
Bulbine natalensis
black gram
banyan
ba ji tian
barbasco
bee products
Borassus aethiopum
banana
Boerhavia diffusa
Calochortus
Curculigo orchioides
cohosh
Clary sage
Chinese mountain ant
Cucurbita
cod liver oil
Codonopsis
Cnidium
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Cyathula
Chinese pond turtle
Chlorophytum
chuchuhuasi
casticin
Campylandra fimbriata
catuaba
costus
Carthamus
Canscora
DHEA
daidzein
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dong quai
dibenzo-alpha pyrones
D-Pinitol
diosgenin
date
eurycomanone
egg
Euryale seed
elk antler
Eurycoma Longifolia
eicosapentaenoic acid
Embelia
estrogen
folic acid
Flueggea suffruticosa
fo-ti
furostanols
formononetin
fish
fatty acids
false unicorn root
Fadogia agrestis
Ginsenosides
Guava
giant trillium
horny goat weed
Herb Robert
Indian sarsparilla
isoflavones
long pepper
icariin
Indian fagonia
inositol phosphate
jungli-bean
Jatropha macrantha
Kachnar
Kokilaksha
Lycium
Lilium polyphyllum
ligustilides
lodhtree
lotus
Leptadenia
Laminaria
lipids
Labisia pumila
macamides
maral root
Mezoneuron benthamianum
Montanoa tomentosa
Matico
Matapalo Tree
Miroestrol
Marine fat
mandrake
Millettia
macaenes
Nigella seed
Ocotillo
Orchis latifolia
orchid
Osthole
Puerain
Phyllanthus
Puerarin
Piper chaba
Propionyl-L-Carnitine
polyunsaturated fat
Protodioscin
probiotics
Phlomis umbrosa
Paris polyphylla
Pedalium
Portulaca
Phytoestrogens
Polygonum
Petiveria
Peptides
rue
Rubus
Rehmannia
Rhaponticum
Rosa laevigata
Sapogenin
Sichuan Lovage
Soy
Selenomethionine
Salvia
Sensitive Plant
Sanguisorba
Safed musli
Shataverins
Shilajit
Sparganium
Tree of heaven
Trichilia catigua
Tynanthus panurensis
Tribulus Terrestris
Vegetable Protein
Vitexicarpin
Viburnum
Vidanga
Vitex Agnus-Castus
Withanolides
Yohimbine
Zedoary

Products containing Tongkat ali