Evidence supporting the use of: Saw palmetto
For the body system: Reproductive System
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Saw palmetto (Serenoa repens) is widely used to support the male reproductive system, particularly for symptoms associated with benign prostatic hyperplasia (BPH), a noncancerous enlargement of the prostate gland. The traditional use of saw palmetto by Native American populations included treatment of urinary and reproductive system issues. In modern times, its use has been primarily focused on alleviating lower urinary tract symptoms related to BPH, such as frequent urination, decreased urinary flow, and nocturia.
Scientific studies on saw palmetto extract have produced mixed results. Some randomized controlled trials and meta-analyses suggest that saw palmetto may offer modest improvements in urinary symptoms and flow measures compared to placebo, though it is generally less effective than standard pharmaceutical treatments such as alpha-blockers and 5-alpha-reductase inhibitors. The proposed mechanism of action includes inhibition of 5-alpha-reductase, the enzyme that converts testosterone to dihydrotestosterone (DHT), a hormone that contributes to prostate enlargement. However, several large, well-conducted studies (e.g., the STEP and CAMUS trials) found no significant difference between saw palmetto and placebo for BPH symptoms.
Overall, saw palmetto is justified as a reproductive system support agent based on both its traditional use and some scientific evidence, though the clinical benefits appear to be modest and inconsistent. It is generally considered safe for short-term use, but more research is needed to clarify its efficacy and long-term safety.
Other ingredients that support Reproductive System
acetyl l-carnitineamino acids
ashwagandha
beta-sitosterol
black cohosh
bovine
bovine liver
broccoli
calcium
chaste tree
Chinese salvia root
choline
coenzyme Q10 (CoQ10)
turmeric
damiana
DHA (docosahexaeonic acid)
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
EPA (eicosapentaenoic acid)
evening primrose oil
fennel
fenugreek
fish protein
flaxseed
folate
gamma linolenic acid (GLA)
ginger
ginseng
gokhru
hops
inositol
iodine
iron
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
l-arginine
l-carnitine
lactobacillus crispatus
lactobacillus jensenii
licorice root
lignans
linoleic acid (LA)
maca
magnesium
marine lipid
melatonin
moringa
motherwort
muira puama
omega-3 fatty acids
omega-6 fatty acids
pomegranate
protein
pumpkin
quail egg
raspberry
rehmannia glutinosa
saffron
saw palmetto
selenium
selenium
soybean
spearmint leaf
tongkat ali
tribulus
vitamin A
vitamin B
vitamin D
vitamin E
vitamin E
seaweed
water
wild yam
zinc
sarsaparilla
red clover
suma
squawvine
mugwort
nut grass
anise
punarnava
smilax
chaff flower
lingusticum wallichii
yarrow
cistanche
dioscorea
dodder
eucommia
ganoderma
lotus seed
morinda
royal jelly
Equol (proprietary)
guelder rose
trace minerals
anemarrhena asphodeloides
purslane
barrenwort
shepherd's purse
wood betony
hypothalamus
herbal blend (proprietary)
yohimbe
11-Ketotestosterone
25-d-spirosta-3, 5-diene
5-methyltetrahydrofolate glucosamine
8-Prenylnaringenin
Antler
Arachidonic Acid
Achyranthes
Anamu
Alchemilla
Aletris
Anserina
Aerva lanata
Agrimonia pilosa
Agnuside
Ashoka
Ant
Abuta
Allium tuberosum
Animal protein
Blue Cohosh
Babchi
Baliospermum
Black galingale
Beef
Beef liver
Bugbane
Bulbine natalensis
Black Gram
Banyan
Ba Ji Tian
Barbasco
Bee products
Borassus aethiopum
banana
Boerhavia diffusa
Calochortus
Curculigo orchicides
Cohosh
Clary sage
Chinese Mountain Ant
Cucurbita
Cod Liver Oil
Codonopsis
Cnidium
Clerodendrum phlomidis
Cynomorium
Cyathula
Chinese Pond Turtle
Chlorophytum
Chuchuhuasi
Casticin
Campylandra fimbriata
Catuaba
Costus
Carthamus
Canscora
DHEA
Daidzein
Deer Velvet
Dong Quai
Dibenzo-alpha pyrones
D-Pinitol
Diosgenin
Date
Egg
Elk antler
Eicosapentaenoic Acid
Embelia
Estrogen
Isoflavones
Lotus
Orchid
yohimbine
Other body systems supported by saw palmetto
BladderGlandular System
Hair
Male Reproductive System
Prostate
Reproductive System
Urinary System