Evidence supporting the use of: Ligustilide
For the body system: Reproductive System
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Ligustilide is a major bioactive compound found in several traditional Chinese medicinal herbs, most notably Angelica sinensis (Dong Quai) and Ligusticum chuanxiong (Chuanxiong). These herbs have been used for centuries in Traditional Chinese Medicine (TCM) to support the reproductive health of women, with a focus on regulating menstruation, alleviating menstrual pain, and addressing symptoms related to reproductive system imbalances. The traditional use is largely based on empirical practice and TCM theory rather than rigorous scientific validation. Modern research has identified ligustilide as one of the key constituents responsible for some of the biological activities of these herbs, such as anti-inflammatory, antispasmodic, and vasodilatory effects, which could theoretically benefit reproductive health (e.g., by reducing uterine muscle spasms). However, most studies to date have been in vitro or in animal models, and there is a lack of robust clinical evidence directly linking ligustilide to improved reproductive system function in humans. Therefore, while the traditional use is well-documented, scientific validation remains limited, and the evidence supporting its efficacy for reproductive health is modest.
Other ingredients that support Reproductive System
Acetyl L-carnitineamino acids
ashwagandha
beta-sitosterol
black cohosh
bovine
bovine liver
broccoli
calcium
chaste tree
Chinese salvia root
choline
coenzyme Q10 (CoQ10)
turmeric
damiana
DHA (docosahexaeonic acid)
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
EPA (eicosapentaenoic acid)
evening primrose oil
fennel
fenugreek
fish protein
flaxseed
folate
gamma linolenic acid (GLA)
ginger
ginseng
gokhru
hops
inositol
iodine
iron
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
L-arginine
l-carnitine
lactobacillus crispatus
lactobacillus jensenii
licorice root
lignans
linoleic acid (LA)
maca
magnesium
marine lipid
melatonin
moringa
motherwort
muira puama
omega-3 fatty acids
omega-6 fatty acids
pomegranate
protein
pumpkin
quail egg
raspberry
rehmannia glutinosa
saffron
saw palmetto
selenium
selenium
soybean
spearmint leaf
tongkat ali
tribulus
vitamin A
vitamin B
vitamin D
vitamin E
vitamin E
seaweed
water
wild yam
zinc
sarsaparilla
red clover
suma
squawvine
mugwort
nut grass
anise
punarnava
smilax
chaff flower
Szechuan lovage
yarrow
cistanche
dioscorea
dodder
eucommia
ganoderma
lotus seed
morinda
royal jelly
Equol (proprietary)
guelder rose
trace minerals
anemarrhena asphodeloides
purslane
barrenwort
shepherd's purse
wood betony
hypothalamus
herbal blend (proprietary)
yohimbe
25-d-spirosta-3, 5-diene
5-methyltetrahydrofolate glucosamine
8-Prenylnaringenin
antler
arachidonic acid
Achyranthes
anamu
Alchemilla
Aletris
Anserina
Aerva lanata
Agrimonia pilosa
Agnuside
Ashoka
Abuta
Allium tuberosum
animal protein
blue cohosh
babchi
Baliospermum
black galingale
beef
Beef liver
bugbane
Bulbine natalensis
black gram
banyan
ba ji tian
barbasco
bee products
Borassus aethiopum
banana
Boerhavia diffusa
Calochortus
Curculigo orchicides
Cohosh
Clary sage
Chinese Mountain Ant
Cucurbita
Cod Liver Oil
Codonopsis
Cnidium
Clerodendrum phlomidis
Cynomorium
Cyathula
Chinese Pond Turtle
Chlorophytum
Chuchuhuasi
casticin
Campylandra fimbriata
catuaba
Costus
Carthamus
Canscora
DHEA
Daidzein
Deer Velvet
Dong Quai
Dibenzo-alpha pyrones
D-Pinitol
Diosgenin
Date
Eurycomanone
Egg
Euryale seed
Elk antler
Eurycoma Longifolia
Eicosapentaenoic Acid
Embelia
Estrogen
Folic Acid
Flueggea suffruticosa
Fo-Ti
Furostanols
formononetin
Fish
Fatty acids
False Unicorn Root
Fadogia agrestis
Ginsenosides
Guava
Giant Trillium
Horny Goat Weed
Herb Robert
Indian Sarsparilla
Isoflavones
Long Pepper
icariin
Indian Fagonia
Inositol phosphate
Jungli-bean
Jatropha macrantha
Kachnar
Kokilaksha
Lycium
Lilium polyphyllum
Ligustilides
Lodhtree
Lotus
Leptadenia
Laminaria
Lipids
Labisia pumila
Macamides
Maral Root
Mezoneuron benthamianum
Montanoa tomentosa
Matico
Matapalo Tree
Miroestrol
Marine fat
Mandrake
Millettia
Macaenes
Nigella Seed
Ocotillo
Orchis latifolia
Orchid
Osthole
Puerain
Phyllanthus
Puerarin
Piper chaba
Propionyl-L-Carnitine
Polyunsaturated Fat
Protodioscin
Probiotics
Phlomis umbrosa
Paris polyphylla
Pedalium
portulaca
Phytoestrogens
Polygonum
Petiveria
Peptides
Rue
Rubus
Rehmannia
Rhaponticum
Rosa laevigata
Sapogenin
Sichuan Lovage
Soy
Selenomethionine
Salvia
Sensitive Plant
Sanguisorba
Safed musli
Shataverins
Shilajit
Sparganium
Tree of heaven
Trichilia catigua
Tynanthus panurensis
Tribulus Terrestris
Vegetable Protein
Vitexicarpin
Viburnum
Vidanga
Vitex Agnus-Castus
Withanolides
yohimbine
Zedoary
Other body systems supported by Ligustilide
BloodBrain
Circulatory System
Digestive System
Female Reproductive System
Gastrointestinal Tract
Intestinal System
Liver
Muscles
Nerves
Reproductive System
Skin
Uterus