Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Gamma Linolenic Acid (GLA) is an omega-6 fatty acid found in oils such as evening primrose oil, borage oil, and black currant seed oil. Its use to support the reproductive system—particularly in women—has some scientific basis, but the overall quality and quantity of evidence is limited. GLA is often promoted for alleviating symptoms of premenstrual syndrome (PMS) and mastalgia (breast pain), as well as for supporting hormonal balance. Several small clinical trials and reviews have investigated GLA’s role, especially in PMS and cyclical breast pain, hypothesizing that GLA’s anti-inflammatory properties and its role in prostaglandin synthesis may influence reproductive hormone activity and related symptoms. However, meta-analyses and systematic reviews indicate that the benefit is modest at best, with some studies failing to show significant improvements over placebo. There is little robust evidence for GLA’s use in broader reproductive health contexts, such as fertility or menstrual regulation. Most professional guidelines do not recommend GLA as a first-line treatment for reproductive health concerns. In summary, while there is some scientific investigation and limited evidence for GLA’s support of the reproductive system, particularly for PMS and breast pain, the overall support is weak and inconsistent.

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