Evidence supporting the use of: Flax lignans
For the body system: Reproductive System
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Flax lignans, particularly secoisolariciresinol diglucoside (SDG), have a long history of traditional use in supporting female reproductive health, especially in cultures where flaxseed is a dietary staple. Historically, flaxseed has been consumed for its purported benefits in managing menstrual discomfort and menopausal symptoms. This traditional use is likely linked to the lignans’ phytoestrogenic properties, as these compounds can weakly bind to estrogen receptors in the body and potentially modulate estrogenic activity.
However, scientific evidence supporting the use of flax lignans specifically for reproductive system support is limited and mixed. Some small-scale clinical studies and animal research suggest that flaxseed or flax lignans may have mild effects on menstrual cycle regulation and menopausal symptom relief, such as hot flashes, due to their weak estrogenic or anti-estrogenic actions. A few studies have also explored their impact on hormone-related conditions such as polycystic ovary syndrome (PCOS) and endometriosis, but results are preliminary and not conclusive.
Overall, while there is a traditional basis for using flax lignans to support the reproductive system, robust scientific validation is lacking, and more high-quality human studies are needed to confirm these effects.
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beta-sitosterol
black cohosh
bovine
bovine liver
broccoli
calcium
chaste tree
Chinese salvia root
choline
coenzyme Q10 (CoQ10)
turmeric
damiana
DHA (docosahexaeonic acid)
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
EPA (eicosapentaenoic acid)
evening primrose oil
fennel
fenugreek
fish protein
flaxseed
folate
gamma linolenic acid (GLA)
ginger
ginseng
gokhru
hops
inositol
iodine
iron
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
L-arginine
l-carnitine
lactobacillus crispatus
lactobacillus jensenii
licorice root
lignans
linoleic acid (LA)
maca
magnesium
marine lipid
melatonin
moringa
motherwort
muira puama
omega-3 fatty acids
omega-6 fatty acids
pomegranate
protein
pumpkin
quail egg
raspberry
rehmannia glutinosa
saffron
saw palmetto
selenium
selenium
soybean
spearmint leaf
tongkat ali
tribulus
vitamin A
vitamin B
vitamin D
vitamin E
vitamin E
seaweed
water
wild yam
zinc
sarsaparilla
red clover
suma
squawvine
mugwort
nut grass
anise
punarnava
smilax
chaff flower
Szechuan lovage
yarrow
cistanche
dioscorea
dodder
eucommia
ganoderma
lotus seed
morinda
royal jelly
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guelder rose
trace minerals
anemarrhena asphodeloides
purslane
barrenwort
shepherd's purse
wood betony
hypothalamus
herbal blend (proprietary)
yohimbe
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Aerva lanata
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Agnuside
Ashoka
Abuta
Allium tuberosum
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Blue Cohosh
Babchi
Baliospermum
Black galingale
Beef
Beef liver
Bugbane
Bulbine natalensis
Black Gram
Banyan
Ba Ji Tian
Barbasco
Bee products
Borassus aethiopum
banana
Boerhavia diffusa
Calochortus
Curculigo orchicides
Cohosh
Clary sage
Chinese Mountain Ant
Cucurbita
Cod Liver Oil
Codonopsis
Cnidium
Clerodendrum phlomidis
Cynomorium
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Chlorophytum
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D-Pinitol
Diosgenin
Date
Eurycomanone
Egg
Euryale seed
Elk antler
Eurycoma Longifolia
Eicosapentaenoic Acid
Embelia
Estrogen
Folic Acid
Flueggea suffruticosa
Fo-Ti
Furostanols
formononetin
Fish
Fatty acids
False Unicorn Root
Fadogia agrestis
Ginsenosides
Guava
Giant Trillium
Horny Goat Weed
Herb Robert
Indian Sarsparilla
Isoflavones
Long Pepper
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Indian Fagonia
Inositol phosphate
Jungli-bean
Jatropha macrantha
Kachnar
Kokilaksha
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Lilium polyphyllum
Ligustilides
Lodhtree
Lotus
Leptadenia
Laminaria
Lipids
Labisia pumila
Macamides
Maral Root
Mezoneuron benthamianum
Montanoa tomentosa
Matico
Matapalo Tree
Miroestrol
Marine fat
Mandrake
Millettia
Macaenes
Nigella Seed
Ocotillo
Orchis latifolia
Orchid
Osthole
Puerain
Phyllanthus
Puerarin
Piper chaba
Propionyl-L-Carnitine
Polyunsaturated Fat
Protodioscin
Probiotics
Phlomis umbrosa
Paris polyphylla
Pedalium
portulaca
Phytoestrogens
Polygonum
Petiveria
Peptides
Rue
Rubus
Rehmannia
Rhaponticum
Rosa laevigata
Sapogenin
Sichuan Lovage
Soy
Selenomethionine
Salvia
Sensitive Plant
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Safed musli
Shataverins
Shilajit
Sparganium
Tree of heaven
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Tynanthus panurensis
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Viburnum
Vidanga
Vitex Agnus-Castus
Withanolides
yohimbine
Zedoary
