Evidence supporting the use of: DHEA
For the body system: Reproductive System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

DHEA (dehydroepiandrosterone) is an endogenous steroid hormone produced by the adrenal glands, and it serves as a precursor to both androgens and estrogens. Its use in supporting the reproductive system—particularly fertility and sexual function—has been the subject of scientific investigation, especially in women with diminished ovarian reserve or advanced maternal age undergoing assisted reproductive technologies (ART).

Clinical studies suggest that DHEA supplementation may modestly improve ovarian function, increase the number of retrieved oocytes, and potentially enhance pregnancy rates in women with poor ovarian response in IVF cycles. However, these findings are not uniformly supported, and systematic reviews and meta-analyses indicate mixed results, with some benefit noted primarily in specific subgroups of women. In men, there is limited evidence for a significant impact of DHEA on fertility parameters or testosterone levels beyond those with adrenal insufficiency.

While DHEA’s role in reproductive health has a scientific basis, the evidence is moderate (rated 3/5) and not universally accepted in clinical guidelines. Its use should be individualized and supervised by healthcare professionals, given potential side effects and contraindications. DHEA is not widely recommended for all individuals seeking reproductive support, but it remains an area of ongoing research for select populations.

More about DHEA
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Products containing DHEA

We currently have no products on Caring Sunshine that contain this ingredient.