Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Acetyl L-carnitine (ALCAR) is supported by scientific evidence for its potential benefits in male reproductive health, particularly concerning sperm quality and male infertility. Several clinical studies have investigated its effects, often in combination with L-carnitine. Research suggests that ALCAR can improve sperm motility, concentration, and overall semen quality in men with idiopathic infertility, possibly due to its antioxidant properties and role in cellular energy metabolism within the reproductive tract. For example, randomized controlled trials have found that supplementation with ALCAR (sometimes alongside L-carnitine) results in statistically significant improvements in sperm parameters and, in some cases, pregnancy rates. Mechanistically, ALCAR is thought to support mitochondrial function in sperm cells, reducing oxidative stress-induced damage to sperm DNA and membranes. However, the evidence is less robust for female reproductive health, and not all studies have found consistent benefits. Guidelines in some countries recommend carnitine supplementation as an adjunct in treating male infertility. Despite these positive findings, more large-scale, well-designed studies are needed to determine optimal dosing and long-term efficacy. Overall, ALCAR holds scientific promise as a supportive agent in male reproductive health, but it is not a primary treatment and should be used under medical supervision.

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Nature's Sunshine Solstic Cardio