Evidence supporting the use of: Sennoside
For the body system: Rectum

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Sennoside is a compound derived from the Senna plant and is widely recognized for its use as a stimulant laxative. There is substantial scientific evidence supporting its effectiveness in promoting bowel movements, primarily by stimulating peristalsis (the muscle contractions that move stool through the intestines) and increasing water and electrolyte secretion in the colon. Sennoside is commonly used to treat constipation, particularly in cases where short-term relief is needed, such as before medical procedures involving the rectum or colon (e.g., colonoscopy preparation).

The primary action of sennoside is on the large intestine, but its relevance to the rectum comes from its ability to facilitate the passage of stool, thus supporting rectal evacuation and overall bowel health. Numerous clinical studies and authoritative guidelines, including those from the U.S. Food and Drug Administration (FDA) and the American Gastroenterological Association, affirm the efficacy and safety of sennoside when used as directed. It is available over the counter in various laxative products.

While long-term or excessive use can lead to potential side effects such as electrolyte imbalance or dependency, its role in supporting rectal and intestinal function in the context of constipation is well established. Therefore, the use of sennoside to support the rectum and lower gastrointestinal tract is scientifically validated and widely accepted in both clinical practice and pharmacological references.

More about Sennoside
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Products containing Sennoside

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