Probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. Their use for rectal health is supported by a moderate level of scientific evidence, particularly in the context of certain rectal and lower gastrointestinal disorders. Research has shown that specific probiotic strains can help manage symptoms of inflammatory bowel diseases (IBD) such as ulcerative colitis, which primarily affect the rectum and colon. For instance, Lactobacillus and Bifidobacterium species have been studied for their ability to reduce inflammation and promote remission in ulcerative colitis patients. Additionally, probiotics have shown benefit in reducing the incidence and severity of pouchitis, an inflammation of the rectal pouch created after surgical removal of the colon. Some studies have also explored the use of probiotics in managing constipation and diarrhea, conditions which can directly impact rectal function and health. However, while there is a growing body of evidence supporting their use for general lower GI tract health, the strength and consistency of evidence specifically targeting rectal conditions is moderate, with variable results depending on the probiotic strains and formulations used. Therefore, the use of probiotics to support the rectum is considered scientifically valid, but further research is needed to fully establish their efficacy and determine optimal strains and dosing.