Evidence supporting the use of: Sapindus mukorossi
For the health condition: Rashes and Hives

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Sapindus mukorossi, commonly known as soapnut or reetha, is widely used in traditional medicine systems, particularly Ayurveda and various folk traditions in India and Southeast Asia. Historically, it has been used to treat a variety of skin conditions, including rashes and hives. The fruit contains saponins, which are natural surfactants, and its extracts have been applied topically for their purported cleansing, anti-inflammatory, and antimicrobial effects. Ethnobotanical literature documents its use as a natural remedy to soothe irritated skin, reduce itching, and manage minor dermatological complaints.

However, the evidence base supporting these uses is largely anecdotal and rooted in traditional practice rather than rigorous scientific evaluation. There are a few in vitro studies suggesting mild antimicrobial and anti-inflammatory activities of Sapindus mukorossi extracts, but clinical data specific to its effectiveness for rashes or urticaria (hives) in humans are lacking. No well-controlled trials exist to validate its efficacy or safety for these indications. Thus, the use of Sapindus mukorossi for rashes and hives is justified primarily by tradition, with limited preliminary scientific support that does not rise above a modest evidence level.

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