Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Mahonia species, particularly Mahonia aquifolium (Oregon grape), have a long history of traditional use in herbal medicine for skin conditions such as rashes and hives. In North American and European herbal traditions, Mahonia root and bark have been prepared as topical salves or tinctures and applied to irritated skin, eczema, psoriasis, and nonspecific rashes. The traditional rationale is based on observed anti-inflammatory and antimicrobial properties, as well as the plant's content of berberine and related alkaloids, which are thought to soothe skin irritation and reduce infection. However, high-quality clinical trials specifically evaluating Mahonia for rashes and hives are lacking. Most modern phytotherapy references cite primarily historical use, and while there is some preliminary laboratory evidence of anti-inflammatory activity, robust clinical validation is minimal. As such, its use for rashes and hives is better characterized by tradition than by rigorous scientific evidence. For psoriasis, there is a bit more scientific data, but for general rashes and hives, the evidence remains weak and largely anecdotal.

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