Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Genipap (Genipa americana) is primarily used in traditional medicine systems in South America for various skin conditions, including rashes and hives. Ethnobotanical surveys and traditional healer accounts document the use of genipap fruit pulp, leaves, and extracts as topical applications to soothe inflammatory skin conditions. The rationale is often based on its perceived anti-inflammatory and antimicrobial properties. However, while these uses are well documented in folk medicine, there is limited scientific investigation into the efficacy or mechanism for treating rashes or urticaria (hives) specifically. Some laboratory studies have identified anti-inflammatory and antioxidant compounds in genipap, such as genipin and iridoid glycosides, suggesting possible biological activity that could be relevant to skin inflammation. However, robust clinical trials or scientific validation for its effectiveness in managing rashes or hives are lacking. In summary, genipap’s use for rashes and hives is rooted in traditional practices, with preliminary phytochemical support but insufficient direct scientific evidence.

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