Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Centipeda minima is traditionally used in various Asian medical systems, particularly in Traditional Chinese Medicine (TCM), to address skin conditions such as rashes and hives. Known as "E Bu Shi Cao" in TCM, it has long been valued for its purported ability to clear heat, dispel wind, and reduce toxins—concepts that are often linked to skin eruptions like rashes and urticaria (hives) in TCM theory. Various classical texts and materia medica list Centipeda minima as an herb for external and sometimes internal use in managing pruritic (itchy) skin disorders, although specifics on its preparation and application can vary.

Scientific investigation into Centipeda minima’s efficacy for rashes and hives is limited. A few in vitro and animal studies have explored its anti-inflammatory, anti-allergic, and immunomodulatory properties, primarily focusing on its potential to inhibit histamine release and reduce inflammatory cytokines. However, there are no high-quality clinical trials directly linking its use to effective treatment of rashes or hives in humans. Thus, while traditional use is well documented, scientific validation remains preliminary, leading to a moderate evidence score reflecting a strong historical basis but limited modern clinical proof.

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