Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Semecarpus anacardium, commonly known as the marking nut, has a long history of use in traditional Ayurvedic medicine for a variety of skin disorders, including psoriasis. Classical Ayurvedic texts describe its application in formulations intended to alleviate symptoms of “Kustha” (a term traditionally used for chronic skin diseases, potentially including psoriasis). The plant is believed to possess anti-inflammatory and immunomodulatory properties according to traditional healers, and its oil or processed extracts are often used topically or internally after specific detoxification procedures (Shodhana) to reduce toxicity.

However, scientific validation for its efficacy in treating psoriasis is limited. A few in vitro and animal studies suggest that Semecarpus anacardium exhibits anti-inflammatory and antioxidant activities, which could theoretically benefit inflammatory skin conditions. Nonetheless, direct clinical trials or robust pharmacological studies specifically evaluating its effect on psoriasis in humans are sparse or lacking. The risk of toxicity and allergic reactions is also notable, as the raw nut contains potent irritants. Modern use generally relies on processed forms designed to mitigate these risks.

In summary, while Semecarpus anacardium is traditionally used for psoriasis within Ayurveda, and some preliminary pharmacological activities support potential skin benefits, strong scientific evidence and clinical data to justify its use for this specific condition are not currently available.

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