Evidence supporting the use of: Pomegranate
For the health condition: Psoriasis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Pomegranate (Punica granatum) has been used in traditional medicine systems for centuries, valued for its antioxidant, anti-inflammatory, and antimicrobial properties. In the context of psoriasis—a chronic, inflammatory skin disorder—pomegranate’s traditional uses are mainly based on its perceived ability to reduce inflammation and promote skin healing. Folk remedies in countries like Iran, India, and regions around the Mediterranean have included pomegranate extracts, juice, or oil in topical or oral preparations for various skin ailments, though specific documentation regarding its use for psoriasis is limited and often anecdotal.

There is a growing body of preclinical scientific research suggesting that compounds found in pomegranate, such as punicalagin, ellagic acid, and anthocyanins, possess anti-inflammatory and antioxidant activities. These actions could theoretically benefit psoriatic skin, which is characterized by oxidative stress and inflammation. A few animal studies and in vitro experiments have demonstrated that pomegranate extracts may suppress pro-inflammatory cytokines (such as TNF-α and IL-6) and reduce markers of oxidative damage. However, human clinical trials specifically evaluating pomegranate’s effectiveness for psoriasis are lacking. Thus, while the traditional use is somewhat supported by early scientific findings, robust clinical evidence remains absent, and pomegranate should not be considered a substitute for established psoriasis treatments.

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