Omega Blend supplements typically contain a combination of omega-3 and sometimes omega-6 and omega-9 fatty acids, most often derived from fish oil, flaxseed oil, or other plant sources. There is a moderate body of scientific evidence suggesting that omega-3 fatty acids, particularly EPA and DHA from fish oil, may have beneficial effects in managing psoriasis, an inflammatory skin condition. Several clinical trials and meta-analyses have examined the use of omega-3 supplements in psoriasis patients. Some studies have found that supplementation can lead to modest improvements in psoriasis severity, likely due to the anti-inflammatory properties of omega-3 fatty acids, which can help modulate immune responses and reduce skin inflammation.

However, the overall quality of the evidence is mixed, with some trials showing significant benefits and others showing minimal or no effect. The American Academy of Dermatology recognizes that omega-3s may be beneficial for some patients but does not recommend them as a primary treatment due to inconsistent results and the need for larger, high-quality studies. There is no strong evidence specifically supporting commercial Omega Blend products over single-source omega-3 supplements. In summary, while there is scientific rationale and some supportive clinical data, the evidence base is moderate at best, justifying a cautious rating and suggesting that omega supplementation may be considered as an adjunct rather than a primary therapy for psoriasis.