Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Grapeseed oil is sometimes used as a complementary topical treatment for psoriasis, primarily due to its emollient properties and content of polyunsaturated fatty acids, such as linoleic acid, as well as vitamin E and antioxidant compounds. Scientific evidence supporting its use for psoriasis is limited but not nonexistent. A few studies have explored the anti-inflammatory and barrier-repairing effects of grapeseed oil when applied to the skin. For instance, linoleic acid, a major component of grapeseed oil, has been shown to improve skin barrier function and reduce inflammation in general dermatological contexts. However, direct studies on grapeseed oil for psoriasis are scarce, and most evidence is extrapolated from its effects on skin moisturization and its anti-inflammatory potential. Some small-scale studies and reviews suggest that grapeseed oil can help reduce skin dryness and irritation, which are common symptoms of psoriasis. Its antioxidant content may also help reduce oxidative stress in the skin, a factor implicated in psoriasis pathogenesis. However, large, high-quality clinical trials specifically evaluating grapeseed oil for psoriasis are lacking. In summary, while there is some mechanistic and preliminary evidence that grapeseed oil could support symptom management in psoriasis due to its moisturizing and anti-inflammatory properties, robust scientific validation is limited. Its use is generally as an adjunct moisturizer rather than a primary treatment.

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