Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bee propolis has been investigated for its potential benefits in treating psoriasis, primarily due to its known anti-inflammatory, antioxidant, and immunomodulatory properties. Laboratory and animal studies have shown that propolis and its key components, such as caffeic acid phenethyl ester (CAPE), can suppress inflammatory cytokines and reduce oxidative stress, both of which are implicated in the pathogenesis of psoriasis. For example, preclinical studies have demonstrated that propolis extracts may decrease levels of TNF-α, IL-1β, and other pro-inflammatory mediators in skin models.

Human evidence, however, is limited. Small pilot studies and case reports suggest that topical application of propolis-containing formulations may improve symptoms like scaling, redness, and itching in psoriatic plaques. A few clinical trials have used propolis in combination with other therapies and reported some improvements, but these trials often lack controls, have small sample sizes, or use mixed preparations, making it difficult to attribute benefits specifically to propolis.

In summary: While there is a scientific rationale for the use of bee propolis in psoriasis based on its biological activities and some encouraging preliminary results, robust clinical evidence is lacking. The overall rating for supporting evidence is therefore low (2 out of 5), reflecting promising but as yet inconclusive data. More rigorous, placebo-controlled human trials are needed to confirm efficacy and safety for this indication.

More about Bee Propolis
More about Psoriasis

Other ingredients used for Psoriasis

Other health conditions supported by Bee Propolis

Products containing Bee Propolis