Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Bovine sources, particularly bovine-derived digestive enzymes such as pancreatin and pepsin, are scientifically validated for supporting protein digestion in individuals with poor digestive function. Pancreatin is a mixture of digestive enzymes (including protease, amylase, and lipase) extracted from the pancreas of cows (bovine). These enzymes are commonly used in enzyme replacement therapy for individuals with exocrine pancreatic insufficiency, a condition characterized by poor digestion, especially of proteins. Clinical studies have demonstrated that bovine pancreatin supplementation improves protein absorption and reduces symptoms such as bloating and steatorrhea in patients with pancreatic insufficiency or chronic pancreatitis. Additionally, bovine pepsin, an enzyme derived from the stomach lining of cows, is used in some digestive aids to mimic the activity of human gastric pepsin, helping to break down proteins into peptides in the stomach. Both ingredients are included in over-the-counter digestive enzyme supplements and have established safety profiles when used as directed. While the strongest evidence exists for medically supervised use in diagnosed enzyme deficiencies, there is also support for their use in more general cases of poor protein digestion. Thus, the use of bovine-derived digestive enzymes for protein digestion is supported by scientific evidence, with several clinical studies and decades of therapeutic use backing their efficacy.

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