Evidence supporting the use of: Quercetin
For the health condition: Prostatitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Quercetin, a flavonoid found in many fruits and vegetables, has been studied for its potential benefits in managing chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). The scientific justification for its use is primarily based on its anti-inflammatory and antioxidant properties. Several clinical studies have investigated quercetin's efficacy in men with CP/CPPS, a condition often characterized by pelvic pain and urinary symptoms without an obvious infection. The most notable evidence comes from a randomized, double-blind, placebo-controlled trial published in 1999 in Urology, where 500 mg of quercetin twice daily for four weeks resulted in significant improvement in symptoms compared to placebo (Nickel et al., 1999). Patients experienced marked reductions in pain and other symptom scores. The proposed mechanisms include quercetin's ability to inhibit the production of pro-inflammatory cytokines and reduce oxidative stress in prostatic tissue. Subsequent smaller studies and anecdotal reports have supported these findings, though the overall body of evidence remains limited by sample size and study duration. Quercetin is not a traditional remedy for prostatitis in the sense of longstanding historical use in folk medicine; rather, its use in this condition is a relatively modern, science-driven development. While the evidence is promising, larger and longer-term studies are needed to confirm both efficacy and safety in diverse populations.

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