Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Soy protein has been investigated for its potential benefits in supporting prostate health, primarily due to its content of isoflavones, such as genistein and daidzein. These phytoestrogens have been proposed to exert protective effects against prostate cancer and benign prostatic hyperplasia (BPH). Epidemiological studies have observed lower rates of prostate cancer in populations with high soy intake, such as in several Asian countries. Clinical studies and meta-analyses have reported modest but statistically significant reductions in prostate-specific antigen (PSA) levels and possible risk reduction for prostate cancer among men consuming higher amounts of soy protein or isoflavones. However, the evidence is not entirely consistent, with some clinical trials showing no clear benefit. The mechanism is thought to involve the modulation of hormone activity, antioxidant properties, and the ability of isoflavones to inhibit pathways involved in prostate cell proliferation. Overall, while there is some scientific validation for the use of soy protein in supporting prostate health, especially regarding prostate cancer risk reduction, the evidence is moderate rather than strong and more high-quality randomized controlled trials are needed to establish definitive benefits.

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