Polyphenols are a diverse group of naturally occurring compounds found in plants, including fruits, vegetables, tea, coffee, and wine. Their use to support prostate health is primarily justified by emerging scientific evidence rather than longstanding traditional use specific to the prostate. Several studies have investigated the role of polyphenols—particularly those from green tea (catechins), pomegranate, and soy (isoflavones)—in supporting prostate health and potentially reducing the risk of prostate-related disorders, such as benign prostatic hyperplasia (BPH) and prostate cancer.

Laboratory and animal studies have shown that polyphenols can exert antioxidant, anti-inflammatory, and antiproliferative effects on prostate cells. For example, green tea catechins (especially epigallocatechin gallate, EGCG) have been studied for their potential to inhibit prostate cancer cell growth and reduce inflammation. Human studies are more limited, but some clinical trials suggest modest benefits. For example, a few randomized controlled trials have found that green tea extracts may slow progression of prostate cancer in men at high risk or reduce symptoms of BPH. However, results are not always consistent, and more large-scale, high-quality studies are needed to confirm these effects.

In summary, there is moderate scientific justification (evidence score 3/5) for the use of certain polyphenols in supporting prostate health, especially based on mechanistic studies and early clinical trials. However, the overall evidence remains preliminary and does not yet warrant strong clinical recommendations.